new paper from the lab

6 September 2020
new paper from the lab
Gandhi et al. Cell Chem Biol 2020

Our collaboration with the former Urban laboratory over the last few years has yielded this article in Cell Chemical Biology, which shows that pharmacological targetting of Plasmodium falciparum rhomboid proteases by ketoamides is feasible. Inhibition of PfROM4 blocks the entry of the parasite into the host cells and cures the culture, hence establishing Plasmodium rhomboids as new drug targets.

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